Mental Health Treatment

Mental Health TreatmentLittle do most people know, but there exists a medical test that can evidence if mental health treatment, which is most often a drug, will predictably cause adverse reactions in a patient, prior to giving them the drug. Mental Health drugs carry strong FDA warnings of hallucinations, mania, psychosis, suicidal and homicidal actions and thoughts and more tragic consequences. The medical test is available through your physician and you have the right to ask for it. Mental health treatment is, by law, under the established legal boundaries of Informed Consent (the right to know the risks of the treatment and the right to know about the alternative treatment).

The scientific study of drugs (pharma) and genetics (inherited characteristics) is called “Pharacogenomics”. This study looks at how genetic characteristics influence medication response and can evidence the inability of a person’s body, to absorb and utilize a drug.

Individual’s responses to drugs are largely influenced by drug metabolism and the ability to metabolize is influenced by the activity of enzymes (electron transfer agents in pathways of the body that are responsible for metabolism). Added variables are the more than fifty different genes that affect the behavior of the metabolic enzymes. Even more variables exist and they include a group of enzymes that have several different versions of each enzyme due to one’s genetic make-up. There are, also, proteins, within the body that play a role in whether the body can break down and assimilate a drug or whether the drug will simply act as a toxin

Medical science has known about these variables for years and has had a way to test these variables to determine the dangers that the drugs may cause to the individual patient. The public is not made aware that this test exists. This includes testing for drugs that are prescribed for physical ailments as well as mental health symptoms

Ones hereditary characteristics adds up to a lot of variables that determine whether an individual can predict that they are likely to experience the FDA adverse effect warnings of mania, psychosis, hallucinations, sudden death, paranoia, delusions, suicidal thoughts and homicidal thoughts and more.

The absorption, distribution, metabolism or elimination of the drug is all influenced by hereditary factors.

Mental health treatment has no medical test done, prior to the prescribing of the drugs, to determine that an individual needs that drug. It is unlike medical science used for determining a physical ailment and this, most definitely, excludes mental health treatment from the realm of scientific fact. It is a field strewn with opinion. Individuals have the right to full factual information so that they can better their lives. (search through the site www.mentalhealthrights.org to find out more)

The following is a table, from the FDA, of the many factors that can influence whether a drug will cause an adverse response.

Factors Influencing Drug Response

Intrinsic
Genetic
  Absorption, distribution, metabolism, excretion
  Body weight
  Genetic conditions
  Genetic polymorphism of drug-metabolizing enzymes
  Height
  Race
  Receptor sensitivity
  Sex
Physiologic
  Absorption, distribution, metabolism, excretion
  Age
  Alcohol
  Body weight
  Cardiovascular function
  Diet
  Diseases/conditions
  Height
  Kidney function
  Liver function
  Receptor sensitivity
  Smoking
  Stress
Extrinsic
Alcohol
Climate
Culture
  Educational status
  Language
  Socioeconomic factors
Definition/diagnostics
Diet
Diseases/conditions
Drug adherence
Medical practices
Pollution
Smoking
Stress
Sunlight
Therapeutic approach

 

Source of Table: Adapted from the U.S. Food and Drug Administration, U.S. Dept. of Health and Human Services. International Conference on Harmonisation: guidance on ethnic factors in the acceptability of foreign clinical data; availability. Federal Register 1998;63(111):31790–31796. http://www.fda.gov/cder/guidance/2293fnl.pdf. Accessed October 17, 2007.

 

Other source of information: Drugs and Genes

Coriell personalized medicine collaborative https://cpmc.coriell.org/Sections/Medical/DrugsAndGenes_mp.aspx?PgId=216

 

 

Posted in Alternatives, Help-From a Mental Health Rights Advocate, Mental Health News and tagged , , , , , .

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